DR. JOHN M. FRAZIER Dr. John M. Frazier, a member of the scientific and professional cadre of senior executives, is a Senior Scientist in Quantitative Toxicology, Human Effectiveness Directorate, Air Force Research Laboratory, Wright-Patterson Air Force Base, Ohio. He is responsible for guiding the in-house toxicology research activities of the Air Force, with special expertise in risk assessment, mechanisms of toxicity, computer modeling of chemical kinetics, and in vitro toxicity testing. His duties include an active research program in predictive toxicology supported by the Air Force Office of Scientific Research. In addition, he is responsible for identifying research gaps and advancements in the field to effectively use available resources to further the Air Force's leading role in toxicological research. He advises the Director and the Chief Scientist on all aspects of toxicology and biotechnology, and he provides expert technical consultation to other Department of Defense laboratories, the Environmental Protection Agency, the National Institute of Environmental Health Sciences, universities and industry. Since 2000, Dr. Frazier has chaired the AFRL Aerospace Biotechnology Working Group and currently leads a new research initiative in cellular dynamics and engineering. Dr. Frazier was a faculty member at Johns Hopkins University's Division of Toxicology in the Department of Health Sciences from 1973 to 1994. He also served for nine years as Associate Director of the Johns Hopkins Center for Alternatives to Animal Testing, and on numerous boards and panels in government and academia. He is the author of more than 70 peer-reviewed scientific papers and 18 book chapters, has edited six books or monographs, and has organized 20 national and international workshops and conferences. In 1994, Dr. Frazier left Johns Hopkins University and accepted a position as principal scientist for ManTech Environmental Technology Inc. at the Tri-Service Toxicology Laboratory, Wright-Patterson AFB. Dr. Frazier was an associate professor with the Department of Pharmacology and Toxicology at Wright State University's School of Medicine from 1994 to 2005. He is an associate professor in the Department of Biochemistry and Molecular Biology, School of Medicine, Wright State University, and an adjunct professor in the Department of Pharmacology and Toxicology, Michigan State University. He has served as liaison for the Air Force to the National Research Council Committee on Toxicology, the Federal Interagency Coordinating Committee for the Validation of Alternative Methods, and the NATO Technical Research Organization Workgroup 09 - Operational Toxicology. EDUCATION1966 Bachelor of Science degree in physics, Johns Hopkins University, Baltimore, Md. 1971 Doctor of Philosophy in physics, Johns Hopkins University, Baltimore, Md.CAREER CHRONOLOGY1. 1973 - 1980, assistant professor, Division of Toxicology, Department of Health Sciences, Johns Hopkins University, Baltimore, Md. 2. 1980 - 1994, associate professor, Division of Toxicology, Department of Health Sciences, Johns Hopkins University, Baltimore, Md. 3. 1982 - 1989, research scientist, Chesapeake Bay Institute, Johns Hopkins University, Baltimore, Md. (Summer 1983, visiting research scientist, Duke University Marine Laboratory, Beaufort, N.C.)4. 1985 - 1994, Associate Director, Johns Hopkins Center for Alternatives to Animal Testing, Baltimore, Md. 5. 1994 - 1995, Principal Scientist, ManTech Environmental Technology Inc., Tri-Service Toxicology Laboratory, Wright-Patterson AFB, Ohio 6. 1995 - 1997, Senior Scientist, Quantitative Toxicology, Armstrong Laboratory, Wright-Patterson AFB, Ohio7. 1997 - present, Senior Scientist, Quantitative Toxicology, Human Effectiveness Directorate, Air Force Research Laboratory, Wright-Patterson AFB, OhioOTHER ACHIEVEMENTS1994 - 2005, associate professor, Department of Pharmacology and Toxicology, School of Medicine, Wright State University, Dayton, Ohio 2000 - 2003, Chairman of the AFRL Aerospace Biotechnology Working Group, Wright-Patterson AFB, Ohio 2002 - present, adjunct associate professor, Department of Pharmacology and Toxicology, Michigan State University, Lansing2004 - present, External Fellow, The Center for the Study of Biological Complexity, Virginia Commonwealth University, Richmond2005 - present, associate professor, Department of Biochemistry and Molecular Biology, School of Medicine, Wright State University, Dayton, Ohio PROFESSIONAL MEMBERSHIPS AND ASSOCIATIONSSociety of ToxicologyAmerican Association for the Advancement of ScienceSigma XiPhi Beta Kappa (Current as of April 2006)